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Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target
In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich,…
Chapter 13 The value of the imagined biological in policy and society
Attending the World Economic Forum this past week, I was struck by two trends. The first was that brain research has emerged as a hot topic. Not only was brain science or brain health a new theme at the meeting, research on the brain emerged in…
Chapter 13 Swedish teachers’ digital competence – infrastructures for teaching and working
Swedish teachers’ digital competence refers to aspects of teaching as well as teachers’ work in a broader context. In this chapter, 19 Swedish teachers’ digital competence is analyzed as infrastructures for teaching and working, thereby setting…
Chapter 13 Private audiovisual media archives in Greenland: A case study of TV-Aasiaat’s audiovisual archives from the 1990s
The national public service television station in Greenland (Kalaallit Nunaata Radioa & TV, abbreviated KNR) is undergoing a digitization of their non-digital media archives, to be completed in 2024. Yet, when KNR first began broadcasting television…
Chapter 12 DISABLED CHILDREN’S PARTICIPATION IN HEALTHCARE DECISION-MAKING
Disabled children are exposed to a host of remedial treatments, therapies or surgeries seeking to restore the ‘normality’ of their bodies and minds. The Convention on the Rights of the Child (CRC) in its Article 12 entitles children with the ‘right…
Chapter 10 The Territory of Medical Research: Experimentation in Africa's Smallest State
In Para-States and Medical Science, P. Wenzel Geissler and the contributors examine how medicine and public health in Africa have been transformed as a result of economic and political liberalization and globalization, intertwined with…
Chapter 10 Sustainability, Public Security, and Privacy Issues Related to Central Bank Digital Currencies (CBDC)
About 100 central banks are currently researching or developing their own central bank digital currencies (more specifically CBDCs). Two projects have recently entered production. The introduction of a CBDC by at least one major central bank in the…
Chapter 10 One Medicine? Advocating (Inter)disciplinarity at the Interfaces of Animal Health, Human Health, and the Environment
This chapter discusses the recent emergence of advocacy for 'One Health' (OH): the idea that greater interdisciplinarity across the domains of human and animal health research, clinical practice and policy is essential for addressing contemporary…
Chapter 10 Animal, Mechanical, and Me
Organ donation and transplantation is a largely successful treatment used to replace failing organs. However, donation rates have never met the demand for transplantable organs. Biomedical researchers are exploring alternative sources from nonhuman…
Chapter 1 The Nordic model of digital archiving: An introduction
The chapter identifies the Nordic countries and describes the Nordic model of digital archiving. We consider what makes Nordic archiving distinctive. Nordic archiving has developed in very close cooperation with public administration, a cooperation…