Browse Items (1015 total)
Sort by:
Chapter Challenges and New Frontiers in the Paediatric Drug Discovery and Development
Drug discovery and development advances in the last decades allowed to find a treatment for many preventable diseases. However, all too often, children are excluded from these progresses since most of the new medicines have been discovered and…
Chapter Bioreactor-Based Bone Tissue Engineering
Omega-3 (ω-3) and omega-6 (ω-6) are polyunsaturated fatty acids (PUFAs) that play critical role in human health and have to be provided by food. In the brain, PUFAs are also precursors of endocannabinoids. The aim of this chapter is to review the…
Chapter Assessing the Performance of Personal Protective Equipment1
Schistosomiasis is the second most prevalent parasitic disease in the world. Currently, the treatment of this disease relies on a single drug, praziquantel, and due to the identification of resistant parasites, the development of new drugs is urged.…
Chapter 7 Vitamin C in Pneumonia and Sepsis
In humans, ascorbic acid is an essential vitamin, anti-oxidant and co-factor of a variety of metal ion-dependent enzymatic reactions. In this review, the transport of L-ascorbic acid is described from food to target cells. Transport of ascorbic acid…
Chapter 3 Vitamin C Alimentation via SLC Solute Carriers
Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a…
Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target
In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich,…
The Future of the Law of the Sea: Bridging Gaps Between National, Individual and Common Interests
It explores the diverse phenomena which are challenging the international law of the sea today, using the unique perspective of a simultaneous analysis of the national, individual and common interests at stake. This perspective, which all the…
White-Collar Crime in the Shadow Economy: Lack of Detection, Investigation and Conviction Compared to Social Security Fraud
This open access book examines the magnitude, causes of, and reactions to white-collar crime, based on the theories and research of those who have uncovered various forms of white-collar crime. It argues that the offenders who are convicted represent…
Mirage of Police Reform : Procedural Justice and Police Legitimacy
n the United States, the exercise of police authority—and the public’s trust that police authority is used properly—is a recurring concern. Contemporary prescriptions for police reform hold that the public would trust the police more and feel a…
Extended Readings on Copyright
Extended Readings on Copyright is subject to a non-commercial Create Commons license that allows you to add, subtract, and amend as you see fit, provided you extend those terms to any derivative work based on these materials and provided your provide…